| 产品详情 |
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| Product Name | LED209 |
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| Description | Purity >98%. Bacterial pathogens require the conserved membrane histidine sensor kinase (QseC) to detect both host-derived adrenergic signals and the bacterial autoinducer-3 (AI-3), thus activating a signaling cascade that induces virulence gene expression. LED209 is a potent QseC inhibitor that blocks both norepinephrine- and epinephrine-triggered QseC-dependent virulence gene expression at 5 pM in vitro . While LED209 inhibits virulence of enterohemorrhagic E. coli, S. typhimurium, and F. tularensis, it does not inhibit pathogen growth, a highly desirable feature of antimicrobial agents to prevent drug resistance. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-phenyl-4-[[(phenylamino)thioxomethyl]amino]-benzenesulfonamide |
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| Gene, Accession, CAS # | CAS: 245342-14-7 |
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| Catalog # | LS-H8441 |
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| Price | |
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| Order / More Info | LED209 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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