产品详情 |
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Antigenic Specificity | IMP4/SPPL2B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 100ul |
Concentration | 1ug/ul |
Applications | WB, IHC-P, IF(IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IMP4/SPPL2B Polyclonal Antibody. • Target Background: SPPL2b is a 592 amino acid multi-pass membrane protein that contains one protease associated domain and belongs to the GXGD family of aspartic proteases. Localized to the membrane of the Golgi apparatus and to lysosomes, endosomes and the plasma membrane, SPPL2b functions as an intramembrane protease that specifically cleaves the transmembrane domain of TNF? Once cleaved, TNF?releases its intracellular domain, thus triggering the immunity-related expression of cytokines (also known as interleuki |
Immunogen | KLH conjugated synthetic peptide derived from human SPPL2B |
Other Names | IMP4; Signal peptide peptidase-like 2B; Intramembrane protease 4; Protein SPP-like 2B; SPPL2B; SPP2B_HUMAN. |
Gene, Accession # | n/a |
Catalog # | bs-11682R |
Price | |
Order / More Info | IMP4/SPPL2B Antibody from BIOSS ANTIBODIES |
Product Specific References | n/a |
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