| 产品详情 |
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| Product Name | (S)-Equol |
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| Description | Purity >98%. Equol is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzen by human intestinal microflora. The estrogen receptor (ER) agonist activity of the naturally occurring (S)-enantiomer (EC50 = 85 and 65 nM for human ERAlpha and ERBeta, respectively) is similar to that of genistein but exceeds that of daidzein. (S)-Equol preferentially binds ERBeta (Ki = 0.73 nM) and demonstrates approximately 9-fold lower affinity for ERAlpha (Ki = 6.41 nM). (S)-equol is also a potent antagonist of dihydrotestosterone, which has important implications for prostate cancer and other androgen-mediated pathologies. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (S)-3,4-dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol, (-)-Equol, 4',7-Dihydroxyisoflavan, 4',7-Isoflavandiol |
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| Gene, Accession, CAS # | CAS: 531-95-3 |
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| Catalog # | LS-H5677 |
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| Order / More Info | (S)-Equol from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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