| 产品详情 |
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| Product Name | Seriniquinone |
| Description | Purity >98% by NMR, TLC. Seriniquinone is a new natural product isolated from a marine bacterium of the genus Serinicoccus. Displays selective toxicity against a distinct set of cell lines (within the NCI 60 panel) predominantly melanoma. Upon cellular treatment, seriniquinone was found to localize in the endoplasmic reticulum. Within 3 hours cells underwent autophagy followed by death via a caspase-9 apoptotic pathway. The target of seriniquinone was identified as the small protein, dermcidin as determined using an immunoaffinity approach. |
| Size | n/a |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Dinaphthol[2,3-b:2',3'-d]thiophene-5,7,12,13-tetraone |
| Gene, Accession, CAS # | CAS: 22200-69-7 |
| Catalog # | LS-H14840 |
| Price | |
| Order / More Info | Seriniquinone from LIFESPAN BIOSCIENCES INC. |
| Product Specific References | n/a |
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