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Product Name | SGTA, 1-313aa, Human, His tag, E.coli |
Description | Purity: > 95% by SDS-PAGE Format: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol 1mM DTT. . SGTA, also known as SGT or hSGT, is a ubiquitously expressed protein that contains three TPR protein-protein interaction repeats. This protien is believed to function as a component of the androgen receptor (AR)-chaperone-cochaperone complex, acting as a cochaperone involved in androgen signaling. In addition, SGTA functions as a cochaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. On the basis of its role in apoptosis and androgen signaling, SGTA is a potential candidate for PCOS (polycystic ovary syndrome), a disorder characterized by androgen excess, obesity and menstrual disturbances. Recombinant SGTA protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Size | 0.5mg, 100ug, 20ug |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | Small glutamine-rich tetratricopeptide repeat-containing protein alpha, alphaSGT, hSGT, SGT, Small glutamine-rich tetratricopeptide repeat-containing protein alpha Small glutamine rich tetratricopeptide repeat TPR containing alpha, uBP, Vpu binding protein. |
Gene, Accession, CAS # | NP 003012 |
Catalog # | ATGP0533 |
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Order / More Info | SGTA, 1-313aa, Human, His tag, E.coli from ATGen |
Product Specific References | n/a |
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