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Product Name | Recombinant Human Haptoglobin (HP) |
Description | Purity > 85% as determined by SDS-PAGE. MW: 57.3kDa. Full Length of Mature Protein: 19-406aa. N-terminal 6xHis-B2M-tagged. Homo sapiens (Human). As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial; Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | Alternative name (s); Zonulin |
Gene, Accession, CAS # | HP, UniProt: P00738 |
Catalog # | RPC25902 |
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Order / More Info | Recombinant Human Haptoglobin (HP) from BIOMATIK |
Product Specific References | n/a |
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