| 产品详情 |
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| Antigenic Specificity | Complement C5 |
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| Clone | polyclonal |
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| Host Species | Sheep |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | ion exchange purified |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | ID, IHC-P (1:100) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Complement C5 Antibody LS-C41851. Recognizes complement component 5 (C5), a member of the complement system. The complement system consists of a tightly regulated network of proteins. Its activation leads to a sequential cascade of enzymatic reactions, resulting in opsonisation of the pathogens and their removal by phagocytes, as well as cell lysis. Three pathways have been described, the antibody-dependent pathway (classical pathway), the alternative pathway and the lectin activation pathway. The complement system plays a critical role in both innate and adaptive immune responses. It is also involved in tissue regeneration, tumor growth and some human pathologies. Complement component 5 is the initiator of the effector terminal phase of the complement system. C5 convertase cleaves C5 into C5a, a potent anaphylatoxin, and C5b, ultimately resulting in the formation of the multimeric membrane attack complex (MAC) together with the other components of the terminal pathway (C5b-C9). Gives a single arc when tested by immunoelectrophoresis (IEP) against human plasma. The identity has been confirmed by double diffusion against fresh human plasma and a known anti human C5. |
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| Immunogen | Human C5, purified from plasma. |
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| Other Names | C5, Anaphylatoxin C5a analog, CPAMD4, Complement C5, Complement component 5 |
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| Gene, Accession # | C5, Gene ID: 727 |
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| Catalog # | LS-C41851 |
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| Price | |
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| Order / More Info | Complement C5 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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