| 产品详情 |
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| Product Name | IPI-145 |
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| Description | Purity >98%. IPI-145 is a potent inhibitor of the phosphoinositide 3-kinase (PI3K) isoforms PI3KGamma and PI3KDelta (IC50 s = 0.24 and 50 nM, respectively). It is orally bioavailable and selective. As PI3KGamma and PI3KDelta are preferentially expressed in immune cells, IPI-145 has profound effects in collagen-induced and adjuvant-induced arthritis, ovalbumin-induced asthma, and systemic lupus erythematosus animal models. It also has potential applications in immunotherapy and in certain cancers. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 8-chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-1(2H)-isoquinolinone, Duvelisib, INK1197 |
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| Gene, Accession, CAS # | CAS: 1201438-56-3 |
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| Catalog # | LS-H8232 |
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| Order / More Info | IPI-145 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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