产品详情 |
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Product Name | ML 351 |
Description | Selective 12/15 LOX inhibitor (IC50 = 200 nM). Exhibits >250-fold selectivity over related isozymes, 5-LOX, platelet 12-LOX, 15-LOX-2, ovine COX-1, and human COX-2. Protects against oxidative glutamate toxicity in mouse neuronal cells (HT-22) and reduces infarct size in a mouse ischemic stroke model. Purity 98%. MW (observed): 249.27 |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 5-(Methylamino)-2-(1-naphthalenyl)-4-oxazolecarbonitrile |
Gene, Accession, CAS # | CAS: 847163-28-4 |
Catalog # | 6448/25 |
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Order / More Info | ML 351 from TOCRIS BIOSCIENCE
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Product Specific References | n/a |
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