产品详情 |
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Product Name | LH 846 |
Description | Selective inhibitor of casein kinase (CK) 1δ (IC50 values are 290 nM, 1.3 μM and 2.5 μM for CK1δ, ε and α); displays no inhibitory activity at CK2. Inhibits CK1δ-dependent phosphorylation and degradation of PER1 protein. Shown to lengthen the circadian period in U2OS cells, with minimal effect on amplitude. Purity 98%. MW (observed): 316.81 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | N-(5-Chloro-6-methyl-2-benzothiazolyl)benzeneacetamide |
Gene, Accession, CAS # | CAS: 639052-78-1 |
Catalog # | 4896/10 |
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Order / More Info | LH 846 from TOCRIS BIOSCIENCE
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Product Specific References | PubMed: 24424021, 25866393, 28125685 |
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