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| Product Name | Mouse IL-27 Carrier-Free Recombinant Protein |
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| Description | Mouse IL-27 Carrier-Free Recombinant Protein, eBioscience™. IL-27 (Interleukin 27) is a cytokine belonging to the IL-12 family, and is a heterodimeric cytokine composed of EBI3 and p28 subunits. IL-27 is produced by activated dendritic cells and macrophages in response to Toll-like receptor ligands and pro-inflammatory cytokines. IL-27 promotes CD4+ T cell differentiation to the Th1 lineage by inducing expression of the transcription factor T-bet and up regulating IL-12R beta2, which in turn suppresses Th2 and Th17 differentiation and proliferation. IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. IL-27 acts by binding to its receptor WSX-1 and gp130 which results in the |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Control: Assay-Dependent, Functional Assay: Assay-Dependent |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Entrez: 246779; Uniprot: Q8K3I6 |
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| Catalog # | 34-8271-82 |
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| Price | |
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| Order / More Info | Mouse IL-27 Carrier-Free Recombinant Protein from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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