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Product Name | TSLP, 29-159aa, Human, His tag, E.coli (Denatured) |
Description | Purity: > 85% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol . TSLP is a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. TSLP is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants. Recombinant human TSLP protein, fused to His-tag at N-terminus, was expressed in E.coli. |
Size | 100ug, 20ug, 4ug |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | Thymic stromal lymphopoietin |
Gene, Accession, CAS # | NP 149024 |
Catalog # | ATGP2950 |
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Order / More Info | TSLP, 29-159aa, Human, His tag, E.coli (Denatured) from ATGen |
Product Specific References | n/a |
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