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Product Name | Mouse APS Synthetic Peptide |
Description | Mouse APS Synthetic Peptide. APS (adapter protein with Pleckstrin homology and Src homology 2 domains) a member of the Lnk family, is an adaptor protein that is involved in B-cell signaling, insulin signaling, cytoskeletal reorganization. It is tyrosine phosphorylated by JAK2, KIT and other kinases during B-cell receptor stimulation of many different cytokines, chemokines and leukokines. APS has been shown to inhibit the JAK-STAT pathway in collaboration with c-Cbl. It is located in the cytoplasm in pre-PDGF (platelet derived growth factor) stimulated cells and localizes to the plasma membrane and peripheral regions upon PDGF stimulation. This protein is expressed in B-cells and mast cells when detected in haematopoietic cell lines yet is a |
Size | 50 ug |
Concentration | lyophilized |
Applications | Blocking Assay: Assay Dependent, Control: Assay Dependent |
Other Names | Alpha-1-antiproteinase S, Alpha-1-antitrypsin, Alpha-1-proteinase inhibitor |
Gene, Accession, CAS # | Entrez: 23921; Uniprot: Q9JID9 |
Catalog # | PEP-246 |
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Order / More Info | Mouse APS Synthetic Peptide from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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