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| Product Name | Human Thrombopoietin (TPO) Carrier-Free Recombinant Protein |
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| Description | Human Thrombopoietin (TPO) Carrier-Free Recombinant Protein, eBioscience™. Thrombopoietin (TPO, THPO, MPL ligand, megakaryocyte colony-stimulating factor) is responsible for the generation of platelets through its action on hematopoietic cells committed to the megakaryocyte lineage. Binding of thrombopoietin to its receptor, MPL (CD110), initiates a signaling cascade via JAK/STAT, MAPK, and PI3K/AKT signaling pathways that leads to the proliferation and differentiation of megakaryocytes and, ultimately, to the production of platelets (thrombopoiesis). Thrombopoietin is constitutively produced by the liver and has a predicted molecular weight of 38 kDa. |
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| Size | 10 µg |
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| Concentration | lyophilized |
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| Applications | Control: Assay-Dependent, Functional Assay: Assay-Dependent |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Entrez: 7066; Uniprot: P40225 |
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| Catalog # | 34-8685-63 |
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| Order / More Info | Human Thrombopoietin (TPO) Carrier-Free Recombinant Protein from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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