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| Product Name | Recombinant Pseudomonas aeruginosa Protease lasA (lasA) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 36kDa. Full Length of Mature Protein: 237-418aa. N-terminal 6xHis-SUMO-tagged. Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228). Involved in proteolysis and elastolysis (degradation of the host protein elastin). Has staphylolytic activity (degrades pentaglycine cross-links in cell wall peptidogylcan), preferring Gly-Gly-|-X substrates where X is Ala or Gly (PubMed:11179971). Enhances the elastolytic but not proteolytic activity of elastase (lasB) and elastolytic activity of other proteases (PubMed:2110137). Degradation of host elastin is likely to contribute to the pathogenicity of P.aeruginosa. While either His-317 or His-356 can abstract a proton in the hydrolysis reaction, the same residue performs both functions in a given catalytic cycle, with the other stabilizing the catalytic intermediate |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Staphylolytic protease |
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| Gene, Accession, CAS # | lasA, UniProt: P14789 |
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| Catalog # | RPC20467 |
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| Order / More Info | Recombinant Pseudomonas aeruginosa Protease lasA (lasA) from BIOMATIK |
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| Product Specific References | n/a |
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