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Product Name | FAM84B, 1-310aa, Human, His tag, E.coli |
Description | Purity: > 85% by SDS - PAGE Format: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.15M NaCl,1mM DTT, 0.1mM PMSF. FAM84B, as known as Family with sequence similarity 84, member B, coprecipitated with a downstream effector of RAS, CRAF. Binding of FAM83B with CRAF disrupted CRAF/14-3-3 interactions and increased CRAF membrane localization, resulting in elevated MAPK and mammalian target of rapamycin (mTOR) signaling. It is an oncogene and potentially represents a new target for therapeutic intervention. Recombinant human FAM84B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
Size | 0.5mg, 100ug, 20ug |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | Family with sequence similarity 84 member B, Family with sequence similarity 84, member B, BCMP101, NSE2 |
Gene, Accession, CAS # | NP 777571 |
Catalog # | ATGP2442 |
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Order / More Info | FAM84B, 1-310aa, Human, His tag, E.coli from ATGen |
Product Specific References | n/a |
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