| 产品详情 |
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| Product Name | Necrosis Inhibitor, Necrox-5 |
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| Description | Purity ~95% (HPLC). A cell-permeable necrosis inhibitor that displays antioxidant property. It localizes mostly in the mitochondria. Selectively blocks oxidative stress-induced necrotic cell death (0.1uM NecroX-5 prevented ~50% cell death in H9C2 cells exposed to 400uM t-BuOOH for 2 hours). Does not protect against staurosporine or etoposide-induced apoptosis. Protects cells against cold shock, hypoxia and oxidative stress in vitro, as well as CCl4 -induced acute liver injury and chronic liver fibrosis in rodent models. Formula: C25H31N3O3S2 ?2CH4O3S Solubility: DMSO (~10mg/ml) or H2O (~10mg/ml) Molecular Weight: ~645.83 |
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| Size | 1mg, 5mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Necrosis Inhibitor, Necrox-5 ([5-(1,1-Dioxo-thiomorpholin-4-ylmethyl)-2-phenyl-1H-indol-7-yl]-(tetrahydro-pyran-4-ylmethyl)-amine, Dihydrochloride) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 170016 |
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| Order / More Info | Necrosis Inhibitor, Necrox-5 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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