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| Product Name | Mouse IL-17F ELISA |
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| Description | IL-17F and 17A are closely related members of the IL-17 cytokine family, sharing about 50% amino acid identity. Expression of IL-17F and IL-17A has been detected in activated human peripheral blood lymphocytes. It has been shown that the cytokines are expressed in activated human CD4+ T cells. Expression of IL-17F and IL-17A has also been observed in tissue samples from various autoimmune diseases such as rheumatoid arthritis, multiple sclerosis, psoriasis, inflammatory bowel disease, and asthma. The crystal structure of IL-17F has been solved and shows that the protein forms a disulfide-linked dimeric glycoprotein. IL-17A is also a disulfide-linked homodimeric glycoprotein. The IL-17F homodimer includes a classical cysteine knot motif, which is found in the TGF-beta, bone morphogenetic protein, and nerve growth factor superfamilies. One difference in the cysteine knot motif of IL-17F compared with the other known cysteine knot protein families is that it only utilizes four cysteines instead of the classical six cysteines to form the knot. IL-17F and IL-17A have been shown to form biologically active IL-17F/IL-17A heterodimers, in addition to the IL-17F and IL-17A homodimers. Sample Types: cell culture, EDTA plasma, serum. Sample Size: 50 µL. Range: 62.5 - 4,000 pg/mL. Sensitivity: 10 pg/mL. Time: 4hr 30min |
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| Size | 96 wells |
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| Concentration | n/a |
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| Applications | Immunoassays. Research Use Only. Not for Use in Diagnostic Procedures. |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 61-ILFMS-E01 |
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| Order / More Info | Mouse IL-17F ELISA from ALPCO |
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| Product Specific References | n/a |
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