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| Product Name | PtdIns-(1,2-dioctanoyl) (sodium salt) |
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| Description | Purity >98%. The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(1,2-dioctanoyl) is a synthetic analog of natural phosphatidylinositol (PtdIns) containing C8:0 fatty acids at the sn -1 and sn -2 positions. The compound features the same inositol and diacyl glycerol (DAG) stereochemistry as that of the natural compound. The short fatty acid chains of this analog, compared to naturally-occurring PtdIns, gives it different physical properties including high solubility in aqueous media. PtdIns are phosphorylated to mono- (PtdIns-P; PIP), di- (PtdIns-P2 ; PIP2 ), and triphosphates (PtdIns-P3 ; PIP3 ). Hydrolysis of PtdIns-(4,5)-P2 by phosphoinositide (PI)-specific phospholipase C generates inositol triphosphate (IP3 ) and DAG which are key second messengers in an intricate biochemical signal transduction cascade. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 1-(1,2-dioctanoylphosphatidyl)inositol, monosodium salt, DOPI, Phosphatidylinositol C-8 |
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| Gene, Accession, CAS # | CAS: 899827-36-2 |
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| Catalog # | LS-H9546 |
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| Order / More Info | PtdIns-(1,2-dioctanoyl) (sodium salt) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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