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Product Name | FEN1, 1-380aa, Human, E.coli |
Description | Purity: > 90% by SDS - PAGE Format: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT 10% glycerol . FEN-1, also known as Flap structure-specific endonuclease 1, removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. FEN-1 is highly homologous to yeast Rad2. The C-terminal region of FEN-1 may bind to PCNA, thus allowing FEN-1 to function as an exonuclease in DNA replication. Recombinant human FEN-1 protein was expressed in E.coli and purified by using conventional chromatography techniques. |
Size | 0.5mg, 100ug, 20ug |
Concentration | n/a |
Applications | SDS-PAGE |
Other Names | Flap structure-specific endonuclease 1, FEN-1, MF1, RAD2, Flap structure-specific endonuclease 1 DNase IV, Flap endonuclease 1, Flap structure specific endonuclease 1, hFEN1, Maturation factor 1, |
Gene, Accession, CAS # | NP 004102 |
Catalog # | ATGP0442 |
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Order / More Info | FEN1, 1-380aa, Human, E.coli from ATGen |
Product Specific References | n/a |
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