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| Product Name | Vedolizumab (maB-based) ELISA Assay Kit |
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| Description | This Eagle Biosciences ELISA is based on a Vedolizumab-specific monoclonal antibody (catcher Ab, ImmunoGuide clone19F3). Diluted standards and samples are incubated in the microtiter plate coated with IG-19F3 mAb. After incubation, the wells are washed. A horseradish peroxidase (HRP)-conjugated anti-human IgG antibody is added and binds to the Fc part of Vedolizumab. Following incubation, wells are washed and the bound enzymatic activity is detected by addition of chromogen-substrate. The color developed is proportional to the amount of Vedolizumab in the sample or standard. Results of samples can be determined by using the standard curve. Sample Types: serum, plasma. Range: 6 - 200 ng/mL. Sensitivity: 5 ng/mL. Time: 2 hours • The drug Vedolizumab (trade name Entyvio®) is a humanized immunoglobulin G1 monoclonal antibody that binds exclusively to the lymphocyte integrin α4β7. Identification of biomarkers might be beneficial for (non-) response and risk factors for adverse drug reactions that might be related to serum drug levels and maintaining the effective concentration in order to potentially avoid some side effects with a reliable method. The specificity of this testsystem is achieved by using a monoclonal antibody named IG-19F3 for the coating of the microtiter plate. This antibody is specific for Vedolizumab only and does not cross react with other lymphocyte integrin α4β7 catchers. |
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| Size | 1 x 96 well |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Vedolizumab, Entyvio |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | IG-AB116 |
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| Order / More Info | Vedolizumab (maB-based) ELISA Assay Kit from EAGLE BIOSCIENCES INC. |
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| Product Specific References | n/a |
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