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Product Name | Human IL-17A Recombinant Protein |
Description | Human IL-17A Recombinant Protein. Interleukin-17A (IL-17A, CTLA-8) is a CD4+ T cell-derived cytokine that promotes inflammatory responses in cell lines and is elevated in rheumatoid arthritis, asthma, multiple sclerosis, psoriasis, and transplant rejection. IL-17A is a 32 kDa long, disulfide-linked homodimer consisting of 136 amino acids that is a member of a six-species family of proteins (IL-17A-17F) and signals through the IL-17 receptor (IL-17R/CDw217). High levels of IL-17A homodimer are produced by activated peripheral blood CD4+ T-cells, and IL-17A also enhances expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts. In particular, human IL-17A also stimulates epithelial, endothelial, or fibroblastic cells |
Size | 20 ug |
Concentration | lyophilized |
Applications | Control: Assay Dependent, ELISA: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent |
Other Names | CTLA8; IL-17; IL-17A; IL17 |
Gene, Accession, CAS # | Entrez: 3605; Uniprot: Q16552 |
Catalog # | RIL1720 |
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Order / More Info | Human IL-17A Recombinant Protein from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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