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| Product Name | Tenuazonic Acid |
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| Description | Purity >98%. Tenuazonic acid is one of the major Alternaria mycotoxins commonly found as a natural contaminant in food (LD50 = 548 µg/egg in the chicken embryo toxicity assay). Tenuazonic acid contamination has been linked to esophageal cancer in human populations at risk of high exposure. Mice fed 100 mg/kg/day tenuazonic acid orally for 10 months developed precancerous lesions on the esophageal mucosa. Microscopic analysis of mucosal epithelial cells from these tenuazonic acid-treated animals reveal pyknosis and marked pleomorphisms in the nuclei, chromatin granulation and increased chromatin mass, irregularities in nuclear contours, and vacuolization in nucleoplasms. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-acetyl-1,5-dihydro-4-hydroxy-5S-[(1S)-1-methylpropyl]-2H-pyrrol-2-one, monocopper salt, AAC-toxin |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | LS-H10154 |
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| Order / More Info | Tenuazonic Acid from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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