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| Product Name | Caspase-3 Assay Kit (Fluorometric) |
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| Description | Caspases are members of the aspartate-specific cysteinyl protease family that play a central role in apoptosis. Apoptosis is involved in a variety of physiological and pathological events, ranging from normal fetal development to diseases such as cancer, organ failure, and neurodegenerative diseases. Caspase-3 is key biomarker in the assessment of apoptosis and in understanding mechanism of apoptosis induction. This Caspase-3 Assay Kit provides a convenient means to measure caspase-3 activity in biological samples. In the assay, a specific substrate (N-Ac-DEVD-AFC) is cleaved by active caspase-3, forming a highly fluorescent product.The fluorescence intensity (lambda ex/em = 400/490nm) is proportional to the caspase-3 activity. Sample types: cell lysates, tissue lysates |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | For quantitative determination of the apoptosis target caspase-3 activity and HTS screen for apoptosis inducers and inhibitors. |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | LS-K252 |
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| Order / More Info | Caspase-3 Assay Kit (Fluorometric) from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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