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| Product Name | HCV-NS5a, 2210-2306aa, Hepatitis C Virus, His tag, E.coli |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% glycerol, 1mM DTT. NS5A is a component of the replication complex involved in RNA-binding. Its interaction with Human VAPB may target the viral replication complex to vesicles. This protein down-regulates viral IRES translation initiation and mediates interferon resistance, presumably by interacting with and inhibiting human EIF2AK2/PKR. NS5a seems to inhibit apoptosis by interacting with BIN1 and FKBP8. The hyperphosphorylated form of NS5A is an inhibitor of viral replication. Recombinant HCV(Hepatitis C Virus) NS5A protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
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| Size | 100ug, 20ug, 4ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Polyprotein, Hepatitis C virus non-structural 5a protein membrane anchor |
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| Gene, Accession, CAS # | NP 671491 |
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| Catalog # | ATGP2739 |
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| Order / More Info | HCV-NS5a, 2210-2306aa, Hepatitis C Virus, His tag, E.coli from ATGen |
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| Product Specific References | n/a |
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