| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | EBV LMP2A |
|---|
| Clone | 15F9 |
|---|
| Host Species | Rat |
|---|
| Reactive Species | epstein-barr virus |
|---|
| Isotype | IgG1 |
|---|
| Format | affinity purified |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | IHC, IHC-P, WB (1:100 - 1:1000) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | EBV LMP2A Antibody (clone 15F9) LS-C57991. Recognizes latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV). EBV is a human herpesvirus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals. Recognizes LMP2A and does not cross react with LMP2B. |
|---|
| Immunogen | Bacterial TrpE-LMP2A fusion protein. |
|---|
| Other Names | n/a |
|---|
| Gene, Accession # | n/a |
|---|
| Catalog # | LS-C57991 |
|---|
| Price | |
|---|
| Order / More Info | EBV LMP2A Antibody from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|