| 产品详情 |
| Edit |   |
| Antigenic Specificity | CD80 |
| Clone | 3H5 |
| Host Species | Mouse |
| Reactive Species | rat |
| Isotype | IgG1 |
| Format | fluorescein (FITC) conjugate |
| Size | n/a |
| Concentration | n/a |
| Applications | Flo (1:1), IHC, IHC-Fr, IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD80 Antibody (clone 3H5, FITC) LS-C188420. Recognizes rat CD80, otherwise known as B7-1, a type I transmembrane glycoprotein and member of the Ig superfamily, which acts as a ligand for both CD28 and CD152 (CTLA-4), and is primarily expressed on antigen presenting cells (APCs) including dendritic cells. CD80 is a B cell activation antigen, which functions in the CD28-CD80/CD86 co-stimulatory pathway vital for T cell activation and proliferation. In contrast, the interaction of CD80 with CD152 has an inhibitory effect on T cell responses. Clone 3H5 has been shown to block the co-stimulatory activity of rat CD80. |
| Immunogen | HTLV-1 transformed Lewis-S1 cells. |
| Other Names | CD80, Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CD80 antigen, LAB7, CD80 molecule, CTLA-4 counter-receptor B7.1 |
| Gene, Accession # | CD80, Gene ID: 941 |
| Catalog # | LS-C188420 |
| Price | |
| Order / More Info | CD80 Antibody from LIFESPAN BIOSCIENCES INC. |
| Product Specific References | n/a |
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