产品详情 |
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Antigenic Specificity | LEF1 Ser42 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 100ul |
Concentration | 1ug/ul |
Applications | WB, IHC-P, IF(IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | LEF1(Ser42) Polyclonal Antibody. • Target Background: Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. May play a role in hair cell differentiation and follicle morphogenesis. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1. Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIAG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1 (By similarity). Isoform 3 lacks the CTNNB1 interaction domai |
Immunogen | KLH conjugated synthetic phosphopeptide derived from human LEF1 around the phosphorylation site of Ser42. Immunogen Range: 14-52/399 |
Other Names | Phosphorylated, phospho-LEF-1; TCF10; TCF7L3; TCF1ALPHA; Lymphoid enhancer-binding factor 1; T cell-specific transcription factor 1-alpha; TCF1-alpha; LEF1 |
Gene, Accession # | Gene ID: 51176, SwissProt: Q9UJU2 |
Catalog # | bs-9842R |
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Order / More Info | LEF1 Ser42 Antibody from BIOSS ANTIBODIES |
Product Specific References | Fu, Qiang, et al. (2016) Int J Mol Sci. PubMed: 27136540 |
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