产品详情 |
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Antigenic Specificity | Wnt-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 30 µg |
Concentration | 0.5 mg/ml |
Applications | Western blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Wnt-1 Antibody. Wnt-1 is a secreted protein that signals throµgh the Frizzled family of cell surface receptors and is required for normal embryonic development. Wnt-1 activation induces a complex signaling cascade that ultimately leads to the increased expression of over fifty genes. An important component of Wnt-1 signaling is the stabilization, and resulting accumulation, of the intracellular signaling protein, beta-catenine. Wnt signaling induces and maintains the transformed phenotype and, in certain embryonic cell lines, supports self renewal in the absence of significant differentiation. Elevated levels of Wnt proteins are associated with tumorigenesis and are present in numerous human breast cancers. Mature human Wnt-1 is a gly |
Immunogen | E. coli expressed human Wnt-1 |
Other Names | wnt1, wnt 1, wnt-1, INT 1 , INT1, wingless type MMTV integration site family member 1 |
Gene, Accession # | Gene ID: 7471, Accession: P04628 |
Catalog # | 5754-30T |
Price | |
Order / More Info | Wnt-1 Antibody from BIOVISION, INC. |
Product Specific References | n/a |
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