产品详情 |
Edit |   |
Product Name | NQO1, 1-274aa, Human, His-tag, E.coli (Bioactivity Validated) |
Description | Purity: > 95% by SDS-PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 1mM DTT. NQO1 is a member of the NAD (P) H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This protein apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. NQO1 functions as an important part of cellular antioxidant defense by detoxifying quinines thus preventing the formation of reactive oxygen species. Altered expression of NQO1 has been seen in many tumors and is also associated with Alzheimer's disease (AD). Recombinant human NQO1, was expressed in E. coli and purified by using conventional chromatography techniques. |
Size | 50ug, 10ug, |
Concentration | n/a |
Applications | SDS-PAGE,Enzyme Activity |
Other Names | NAD(P)H dehydrogenase quinone 1, DHQu, DIA4, DTD, NMOR1, NMORI, QR1, Azoreductase, Quinone reductase 1, DT-diaphorase, NAD(P)H dehydrogenase, quinone 1, Azoreductase.Menadione reductase, NQO 1, QR 1, Phylloquinone reductase, Cytochrome b 5 reductase, DIA 4, Diaphorase (NADH/NADPH), Diaphorase 4 Dioxin inducible 1, DT diaphorase, Diaphorase (NADH/NADPH) (cytochrome b 5 reductase), NAD(P)H dehydrogenase quinone 1 NAD(P)H menadione oxidoreductase 1 dioxin inducible, NAD(P)H: menadione oxidoreductase 1 dioxin inducible 1, NAD(P)H:menadione oxidoreductase 1, NAD(P)H:Quinone acceptor oxidoreductase type 1, NAD(P)H:quinone oxidoreductase 1, NAD(P)H:quinone oxireductase, NMOR 1, NMOR I. |
Gene, Accession, CAS # | NP_000894 |
Catalog # | ATGP3876 |
Price | |
Order / More Info | NQO1, 1-274aa, Human, His-tag, E.coli (Bioactivity Validated) from ATGen |
Product Specific References | n/a |
产品资料 |
|
|