产品名称 NuDT1, 1-156aa, Human, His tag, E.coli from ATGen
产品货号 ATGP0742
产品价格 现货询价,电话:010-67529703
产品规格 0.5mg, 100ug, 20ug
产品品牌 ATGen
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Product NameNuDT1, 1-156aa, Human, His tag, E.coli
DescriptionPurity: > 95% by SDS - PAGE Format: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 2mM DTT, 100mM NaCl. NuDT1 is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. It is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. And this protein expressed at much higher levels in proliferating cells than in resting cells. Recombinant human NuDT1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Size0.5mg, 100ug, 20ug
Concentrationn/a
ApplicationsSDS-PAGE
Other Names78-dihydro-8-oxoguanine triphosphatase, MTH1, 8-oxo-dGTPase, Nudix motif 1, 7,8-dihydro-8-oxoguanine triphosphatase
Gene, Accession, CAS #NP 945191
Catalog #ATGP0742
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Order / More InfoNuDT1, 1-156aa, Human, His tag, E.coli from ATGen
Product Specific Referencesn/a
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