| 产品详情 |
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| Product Name | C-C motif chemokine 19, active (Ccl19), Recombinant, Mouse |
| Description | Purity ≥97% as determined by SDS-PAGE and HPLC. Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Binds to chemokine receptor CCR7. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. Biological Activity: Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human mature dendritic cells is in a concentration range of 10-100ng/ml. |
| Size | 5ug, 20ug, 100ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Epstein-Barr virus-induced molecule 1 ligand chemokine, ELC, Small-inducible cytokine A19 |
| Gene, Accession, CAS # | CCL19_MOUSE, SwissProt: O70460 |
| Catalog # | 347952 |
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| Order / More Info | C-C motif chemokine 19, active (Ccl19), Recombinant, Mouse from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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