| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | ITGAV/Integrin Alpha V/CD51 |
|---|
| Clone | RMV-7 |
|---|
| Host Species | Rat |
|---|
| Reactive Species | mouse |
|---|
| Isotype | IgG1 |
|---|
| Format | affinity purified |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | Flo (1:25 - 1:100), IHC, IHC-Fr (1:25 - 1:100), IP |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | ITGAV/Integrin Alpha V/CD51 Antibody (clone RMV-7) LS-C57970. Recognizes murine CD51, a 140 kD alpha subunit of the vitronectin receptor, which is otherwise known as the integrin alpha v chain. CD51 can form heterodimers at the cell surface with a variety of beta integrins including CD29 and CD61. Heterodimers of CD51/CD61 function as a receptor for vitronectin, and a wide array of RGD-containing proteins including fibronectin, fibrinogen, von Willebrand factor, laminin, thrombospondin and osteopontin. CD51/CD61 is primarily expressed on myeloid cells and activated T-cells. Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity. |
|---|
| Immunogen | Cultured LAK cells from Balb/c mice. |
|---|
| Other Names | ITGAV, CD51, CD51 antigen, Integrin, alpha V, MSK8, Integrin Alpha V, Integrin alpha-V, VNRA, Vitronectin receptor, Integrin alphaVbeta3, VTNR |
|---|
| Gene, Accession # | ITGAV, Gene ID: 3685 |
|---|
| Catalog # | LS-C57970 |
|---|
| Price | |
|---|
| Order / More Info | ITGAV/Integrin Alpha V/CD51 Antibody from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|