| 产品详情 |
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| Antigenic Specificity | ITGAV/Integrin Alpha V/CD51 |
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| Clone | RMV-7 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG1 |
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| Format | phycoerythrin (RPE) conjugate |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | Flo (1:1 - 1:10), IHC, IHC-Fr, IP |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ITGAV/Integrin Alpha V/CD51 Antibody (clone RMV-7, RPE) LS-C57971. Recognizes murine CD51, a 140 kD alpha subunit of the vitronectin receptor, which is otherwise known as the integrin alpha v chain. CD51 can form heterodimers at the cell surface with a variety of beta integrins including CD29 and CD61. Heterodimers of CD51/CD61 functions as a receptor for vitronectin, and a wide array of RGD-containing proteins including fibronectin, fibrinogen, von Willebrand factor, laminin, thrombospondin and osteopontin. CD51/CD61 is primarily expressed on myeloid cells and activated T-cells. Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity. |
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| Immunogen | Cultured LAK cells from Balb/c mice. |
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| Other Names | ITGAV, CD51, CD51 antigen, Integrin, alpha V, MSK8, Integrin Alpha V, Integrin alpha-V, VNRA, Vitronectin receptor, Integrin alphaVbeta3, VTNR |
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| Gene, Accession # | ITGAV, Gene ID: 3685 |
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| Catalog # | LS-C57971 |
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| Price | |
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| Order / More Info | ITGAV/Integrin Alpha V/CD51 Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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