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| Product Name | DUSP26, Recombinant, Human, aa1-211, His-SUMO-Tag (Dual Specificity Protein Phosphatase 26) |
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| Description | Purity ~90% (SDS-PAGE). Inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. Inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. Can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK). Source: Recombinant protein corresponding to aa1-211 from human DUSP26, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~39.9kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Dual specificity phosphatase SKRP3, Low-molecular-mass dual-specificity phosphatase 4, DSP-4, LDP-4 Mitogen-activated protein kinase phosphatase 8, MAP kinase phosphatase 8, MKP-8 Novel amplified gene in thyroid anaplastic cancer |
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| Gene, Accession, CAS # | SwissProt: Q9BV47 |
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| Catalog # | 373110 |
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| Order / More Info | DUSP26, Recombinant, Human, aa1-211, His-SUMO-Tag (Dual Specificity Protein Phosphatase 26) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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