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| Product Name | DUSP18, Recombinant, Human, aa1-188, His-Tag |
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| Description | Purity ~95% (SDS-PAGE). Dual specificity phosphatase 18, also known as DUSP18, is a member of the dual-specificity phosphatase (DSP) family, which catalyzes dephosphorylation of phosphotyrosine and phosphothreonine residues. DUSP18 is inhibited by iodoarectic acid and is activated by manganese ions. Along with having preferential enzymatic activity against phosphorylated tyrosine residues over threonine residues, DUSP18 also dephosphorylates p-nitrophenyl phosphate (pNPP) in vitro. This protein is widely expressed with highest levels in liver, brain, ovary and testis. Source: Recombinant corresponding to aa1-188 from human DUSP18, fused to His-tag at N-terminus, expressed in E.coli. Molecular Weight: ~23.6kD (212aa) confirmed by MALDI-TOF AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMTAPSC AFPVQFRQPS VSGLSQITKS LYISNGVAAN NKLMLSSNQI TMVINVSVEV VNTLYEDIQY MQVPVADSPN SRLCDFFDPI ADHIHSVEMK QGRTLLHCAA GVSRSAALCL AYLMKYHAMS LLDAHTWTKS CRPIIRPNSG FWEQLIHYEF QLFGKNTVHM VSSPVGMIPD IYEKEVRLMI PL |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | DUSP18, Recombinant, Human, aa1-188, His-Tag (Dual Specificity Protein Phosphatase 18, Low Molecular Weight Dual Specificity Phosphatase 20, LMWDSP20) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 45422 |
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| Order / More Info | DUSP18, Recombinant, Human, aa1-188, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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