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| Product Name | DUSP3, Recombinant, Human, aa1-185, His-Tag |
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| Description | Purity ~95% (SDS-PAGE). DUSP3 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein kinase superfamily, which are associated with cellular proliferation and differentiation. DUSP3 is expressed in both breast and ovarian tissues. DUSP3 Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2. Source: Recombinant corresponding to aa1-185 from human DUSP, fused to His-tag at N-terminal expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MSGSFELSVQ DLNDLLSDGS GCYSLPSQPC NEVTPRIYVG NASVAQDIPK LQKLGITHVL NAAEGRSFMH VNTNANFYKD SGITYLGIKA NDTQEFNLSA YFERAADFID QALAQKNGRV LVHCREGYSR SPTLVIAYLM MRQKMDVKSA LSIVRQNREI GPNDGFLAQL CQLNDRLAKE GKLK |
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| Size | 100ug, 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | DUSP3, Recombinant, Human, aa1-185, His-Tag (Dual Specificity Protein Phosphatase 3, Dual Specificity Protein Phosphatase VHR, Vaccinia H1-related Phosphatase, VHR) |
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| Gene, Accession, CAS # | Accession: NP_004081 |
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| Catalog # | D9840-06M |
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| Order / More Info | DUSP3, Recombinant, Human, aa1-185, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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