| 产品详情 |
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| Antigenic Specificity | ITGA6/Integrin Alpha 6/CD49f |
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| Clone | NKI-GoH3 |
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| Host Species | Rat |
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| Reactive Species | mouse, dog, sheep, porcine, cynomolgus, cynomolgus monkey, human, monkey |
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| Isotype | IgG2a |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | Flo (1:25 - 1:50), Func, IHC, IHC-Fr, IP |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ITGA6/Integrin Alpha 6/CD49f Antibody (clone NKI-GoH3, Low Endotoxin) LS-C188732. Recognizes CD49F (VLA-6 alpha chain), a 120kD cell surface glycoprotein that can form distinct complexes with CD29 (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells. Clone NKI-GoH3 reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukaemia cells (alpha-6 beta-1). In immunohistology the monoclonal antibody reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytotrophoblasts. VLA-6 is an important mediator of cell binding to laminin. Studies suggest that clone NKI-GoH3 specifically blocks the binding of cells to the E8 fragment of laminin. |
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| Immunogen | BALB/c mouse mammary tumor cells. |
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| Other Names | ITGA6, CD49f, CD49f antigen, Integrin alpha6B, Integrin, alpha 6, Integrin alpha-6 precursor, VLA-6, Integrin alpha-6, ITGA6B |
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| Gene, Accession # | ITGA6, Gene ID: 3655 |
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| Catalog # | LS-C188732 |
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| Price | |
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| Order / More Info | ITGA6/Integrin Alpha 6/CD49f Antibody from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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