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| Product Name | Neuronal Differentiation Inducer |
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| Description | Purity ~95% (HPLC). A cell-permeable, 8-prenyl flavone that is shown to induce differentiation of mouse embryonic stem (ES) cells into neuronal cells and astrocytes, at 100nM. It is shown to elicit the down-regulation of p38 and JNK phosphorylation, and the up-regulation of ERK phosphorylation. Co-treatment with GGTI-298 (1000nM), a Geranylgeranyltransferase I Inhibitor selectively abolishes the IBA- but not Retinoic Acid-induced neuronal differentiation, which suggests that the differentiation inducing effect may involve protein prenylation. Formula: C20H20O4 Molecular Weight: 324.4 Solubility: DMSO (100mg/ml clear, yellow solution) |
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| Size | 5mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Neuronal Differentiation Inducer (Isobavachin, 7-hydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-enyl)chroman-4-one) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217583 |
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| Order / More Info | Neuronal Differentiation Inducer from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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