| 产品名称 |
IGF1R, Recombinant, Human, His-Tag (Insulin-like Growth Factor 1, CD221, IGFIR, JTK13, MGC142170, MGC142172) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | IGF1R, Recombinant, Human, His-Tag (Insulin-like Growth Factor 1, CD221, IGFIR, JTK13, MGC142170, MGC142172) |
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| Description | Purified (~70-90%). IGF1R (Insulin-like Growth Factor 1) is a transmembrane tyrosine kinase receptor that is activated by IGF-1 and by the related growth factor IGF-2. IGF1R mediates the effects of IGF-1 and plays an important role in growth and anabolic effects in adults. The IGF1R is implicated in several cancers, most notably breast cancer where it is highly overexpressed and functions as an anti-apoptotic agent by enhancing cell survival. In many instances, the anti-apoptotic properties of IGF1R overexpression allows cancerous cells to resist the cytotoxic properties of chemotheraputic drugs or radiotherapy. Source: Recombinant protein corresponding to human IGF1R fused to His-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~53kD Specific Activity: 263nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NM_000875 |
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| Catalog # | 500088 |
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| Price | |
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| Order / More Info | IGF1R, Recombinant, Human, His-Tag (Insulin-like Growth Factor 1, CD221, IGFIR, JTK13, MGC142170, MGC142172) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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