| 产品详情 |
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| Product Name | Doramapimod, Free Base |
| Description | Purity ~90%. Doramapimod is a protein kinase inhibitor with a >330-fold selectivity for p38 MAPK compared with 12 other protein kinases. In contrast to other p38 MAPK inhibitors (e.g., SB203580), doramapimod prevents both the kinetic activity and phosphorylation of p38 MAPK by binding to the ATP pocket as well as to a novel allosteric binding site on p38 MAPK. Solubility: Soluble in DMSO at 50mg/ml. Soluble in ethanol at 33mg/ml. Very poorly soluble in water. Maximum solubility in plain water is estimated to be about 5-20uM. |
| Size | 5mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | Doramapimod, Free Base (1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea) (BIRB 796, DB03044, D03736) |
| Gene, Accession, CAS # | n/a |
| Catalog # | D9023 |
| Price | |
| Order / More Info | Doramapimod, Free Base from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
| 产品资料 |
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