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| Product Name | EED, Recombinant, Human, aa1-441, His-Tag (Embryonic Ectoderm Development) |
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| Description | Purity ~95% (SDS-PAGE). Polycomb protein Embryonic Ectoderm Development (EED) is a WD repeat containing member of the Polycomb-group (PcG) family. The EED protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. EED is an established transcriptional repressor, as a novel NIPP1 interactor. NIPP1 only interacted with full-length EED, whereas two EED interaction domains were mapped to the central and COOH-terminal thirds of NIPP1. In mammalian cells, EED is present as four distinct isoforms, which are believed to be produced by utilizing four distinct, in-frame translation start sites in a common EED mRNA. The extra sex combs (esc) gene of Drosophila and its mammalian homologue embryonic ectoderm development (EED) play pivotal roles in establishing Polycomb-group (Pc-G) mediated transcriptional silencing of regulatory genes during early development. EED/Sox2 regulatory loop contributes to the maintenance of self- |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Embryonic Ectoderm Development |
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| Gene, Accession, CAS # | EED, Gene ID: 8726, Accession: O75530 |
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| Catalog # | 219706 |
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| Order / More Info | EED, Recombinant, Human, aa1-441, His-Tag (Embryonic Ectoderm Development) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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