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| Product Name | AKR7A2, Recombinant, Human, aa1-359, His-Tag |
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| Description | Purity ≥ 95% (SDS-PAGE). Aldo-keto reductases, such as AKR7A2, are involved in the detoxification of aldehydes and ketones. This protein can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the nonbinding AFB1 dialcohol. It may be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. Also, it has been proposed previously to catalyze the NADPH-dependent reduction of succinic semialdehyde (SSA) to Gamma-Hydroxybutyrate in human brain. Source: Recombinant protein corresponding to aa1-359 from human AKR7A2, fused to His-tag, expressed in E. coli. Molecular Weight: ~44kD (398aa, aa1-359 + His Tag) Biological Activity: Specific activity is ~0.25-0.3units/mg. Enzymatic activity was confirmed by measuring the amount of enzyme catalyzing the oxidation of 1 micromole NADPH/minute at 25°C. AA Sequence: MRGSHHHHHH AAVHCALRSP AFLERGHTEL KSLKPDSVRS QLETSLKRLQ CPQVDLFYLH APDHGTPVEE TLHACQRLHQ EGKFVELGLS NYASWEVAEI CTLCKSNGWI |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | AKR7A2, Recombinant, Human, aa1-359, His-Tag (Aldo-keto reductase family 7, member A 2, Aflatoxin B1 aldehyde reductase member 2, AFAR, AFAR1, AFB1-AR1, AKR7) |
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| Gene, Accession, CAS # | Gene ID: 8574, SwissProt: O43488 |
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| Catalog # | 169921 |
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| Order / More Info | AKR7A2, Recombinant, Human, aa1-359, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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