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| Product Name | MCM2, Recombinant, Human, aa2-904, His-Tag (DNA Replication Licensing Factor MCM2) |
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| Description | Purity ~90% (SDS-PAGE). Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division. Source: Recombinant protein corresponding to aa2-904 from human MCM2, fused to His-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~105.8kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Minichromosome maintenance protein 2 homolog, Nuclear protein BM28 |
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| Gene, Accession, CAS # | SwissProt: P49736 |
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| Catalog # | 374165 |
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| Order / More Info | MCM2, Recombinant, Human, aa2-904, His-Tag (DNA Replication Licensing Factor MCM2) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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