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| Product Name | Human FGF-23 protein |
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| Description | Fibroblast growth factor-23 (FGF-23) belongs to the large FGF family which has at least 23 members. All FGF family membersare heparin binding growth factors with a core 120 amino acid (a.a.) FGF domain that allows for a common tertiary structure.FGFs are expressed during embryonic development and in restricted adult tissues. Four distinct but related classes of FGFreceptors, FGF R1, 2, 3, and 4, exist. FGF-23 is produced by osteocytes and osteoblasts in response to high circulating phosphatelevels, elevated parathyroid hormone, and circulatory volume loading. It functions as an endocrine phosphatonin by suppressingcirculating phosphate levels. FGF-23 interaction with renal proximal tubular epithelium decreases the renal resorption ofphosphate by down regulating phosphate transporters and by suppressing vitamin D production. It also decreases the intestinalabsorption of phosphate. MW: 22.5 kDa. Purity > 95% by SDS-PAGE and HPLC analyses |
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| Size | 5 ug, 20 ug, 1 mg, 100 ug, 250 ug, 500 ug |
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| Concentration | Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4. |
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| Applications | HPLC, SDS-PAGE |
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| Other Names | Human Fibroblast Growth Factor-23 protein |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | orb107724 |
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| Price | |
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| Order / More Info | Human FGF-23 protein from BIORBYT LTD. |
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| Product Specific References | n/a |
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