产品名称 Myelin Basic Protein (MBP) (Biotin) from UNITED STATES BIOLOGICAL
产品货号 M9758-10
产品价格 现货询价,电话:010-67529703
产品规格 1mg
产品品牌 UNITED STATES BIOLOGICAL
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Product NameMyelin Basic Protein (MBP) (Biotin)
DescriptionPurified using FPLC liquid chromatography and dephosphorylated using Lambda protein phosphatase. Lambda protein phosphatase was inactivated, in the presence of 10mM sodium EDTA, at 65°C for one hour. Purity was assessed at 95% using SDS-PAGE and Coomassie blue staining of 1ug of product. In vitro, myelin basic protein (MBP) is a substrate for phosphorylation by several different protein kinases including MAPK, PKA, calmodulin-dependent protein kinase, PKC and phosphorylase kinase. Even highly specific protein kinases such as Raf1, MEK and MEKK can utilize MBP as an alternative substrate. Myelin basic protein (MBP) is a single-chain, flexible polypeptide of about 18.5kD existing in its natural environment as an extrinsic and loosely bound component of the cytoplasmic portion of the myelin membrane sandwich. Ultrastructural immunocytochemistry with anti-myelin basic protein has shown that MBP is localized in the compact myelin sheath. MBP has not been demonstrated in rough endoplasmic re
Size1mg
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Catalog #M9758-10
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