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| Product Name | ML 240 |
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| Description | ATP-competitive inhibitor of p97 ATPase (VCP, IC50 = 110 nM). Exhibits antiproliferative activity in NCI-60 cancer cell lines and rapidly induces executioner caspases 3 and 7 in multiple colon cancer cells. Promotes accumulation of LC3-II and impairs autophagosome maturation. Also impairs the endoplasmic-reticulum-associated degradation (ERAD) pathway. Purity 99%. MW (observed): 396.44 |
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| Size | 50 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-(2-Amino-1H-benzimidazole-1-yl)-8-methoxy-N-(phenylmethyl)-4-quinazolinamine |
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| Gene, Accession, CAS # | CAS: 1346527-98-7 |
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| Catalog # | 5153/50 |
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| Price | |
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| Order / More Info | ML 240 from TOCRIS BIOSCIENCE
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| Product Specific References | n/a |
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| 产品资料 |
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