产品详情 |
Edit |   |
Product Name | ML 240 |
Description | ATP-competitive inhibitor of p97 ATPase (VCP, IC50 = 110 nM). Exhibits antiproliferative activity in NCI-60 cancer cell lines and rapidly induces executioner caspases 3 and 7 in multiple colon cancer cells. Promotes accumulation of LC3-II and impairs autophagosome maturation. Also impairs the endoplasmic-reticulum-associated degradation (ERAD) pathway. Purity 99%. MW (observed): 396.44 |
Size | 10 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 2-(2-Amino-1H-benzimidazole-1-yl)-8-methoxy-N-(phenylmethyl)-4-quinazolinamine |
Gene, Accession, CAS # | CAS: 1346527-98-7 |
Catalog # | 5153/10 |
Price | |
Order / More Info | ML 240 from TOCRIS BIOSCIENCE
|
Product Specific References | n/a |
产品资料 |
|
|