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| Product Name | DRAK1, Recombinant, Human, GST-tag |
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| Description | Purified (~70-90%). DRAK1 (STK17A) is a member of the DAP kinase-related apoptosis-inducing protein kinase family. DRAK1 encodes an autophosphorylated nuclear protein with a protein kinase domain which has apoptosis-inducing activity. DRAK1 is capable of autophosphorylation and of phosphorylating myosin light chain as an exogenous substrate. The noncatalytic C-terminal of DRAK1 is crucial for full kinase activity. DRAK1 is highly expressed in placenta, but also in heart, lung, skeletal muscle, kidney, and pancreas. DRAK1 act as a novel direct target of p53 and a modulator of cisplatin toxicity and reactive oxygen species in testicular cancer cells. Source: Recombinant protein corresponding to human DRAK1, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~83kD Specific Activity: 8.5nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | DRAK1, Recombinant, Human, GST-Tag (DAP Kinase-related Apoptosis-inducing Protein Kinase 1, Serine/Threonine Kinase 17A, STK17A) |
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| Gene, Accession, CAS # | Accession: NM_004760 |
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| Catalog # | 499929 |
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| Order / More Info | DRAK1, Recombinant, Human, GST-tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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