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| Product Name | ML 323 |
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| Description | Potent and selective allosteric inhibitor of USP1-UAF1 deubiquitinase complex (IC50 = 76 nM). Exhibits selectivity for USP1-UAF1 over a panel of enzymes, including other deuquitinating enzymes. Inhibits deubiquitination of PCNA and FANCD2 and sensitizes cisplatin-resistant H596 cells to cell death induced by cisplatin (Cat. No. 2251) in vitro. Purity 98%. MW (observed): 384.48 |
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| Size | 25 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-Methyl-2-[2-(1-methylethyl)phenyl]-N-[[4-(1H-1,2,3-triazol-1-yl)phenyl]methyl]-4-pyrimidinamine |
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| Gene, Accession, CAS # | CAS: 1572414-83-5 |
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| Catalog # | 6435/25 |
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| Price | |
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| Order / More Info | ML 323 from TOCRIS BIOSCIENCE
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| Product Specific References | PubMed: 24531842 |
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| 产品资料 |
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